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Oral Contraceptive Use and Increased Risk of Stroke: A Dose-Response Meta-Analysis of Observational Studies.

Front Neurol · 2019 · PMC6767325 · PMID 31592249

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marginal significanceno p-value reported
Our findings indicated that (1) the increased estrogen dosage and duration of OCP use were associated with the increased risk of stroke in women, and the longer duration of OCP cessation was related to less risk of stroke; (2) there was only a marginal significance between duration of OCP use and increased HS risk; (3) there was an approximate linear association of estrogen dosage or OCP cessation but a non-linear association of duration of OCP use with the risk of stroke.

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