Relationship Between Benralizumab Exposure and Efficacy for Patients With Severe Eosinophilic Asthma.

Clin Pharmacol Ther · 2019 · PMC6767326 · PMID 30661249

Europe PMC DOI

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an apparent trendno p-value reported

In a post hoc analysis of the relationship between the number of exacerbations in the previous year with E max , there was an apparent trend of improving FEV 1 for patients with ≥ 3 exacerbations in the previous year.

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a positive trendno p-value reported

There was a positive trend toward improved benralizumab efficacy for patients with greater baseline blood eosinophil counts; however, the effect was not significant.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.