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First detection of Hepatitis E virus (Orthohepevirus C) in wild brown rats (Rattus norvegicus) from Great Britain.

Zoonoses Public Health · 2019 · PMC6767579 · PMID 31033238

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a decreasing trendno p-value reported
The number of reported human HEV infections in Great Britain (GB) had been increasing annually, from 368 cases reported in 2010 to 1,243 in 2016 in England and Wales (PHE, 2018a ), although recent data (2016–2017) show a decreasing trend in the number of hepatitis E cases in England and Wales, with 912 cases reported (PHE, 2018a ).

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