Minimum Inhibitory Concentration Distribution of Fluconazole against Cryptococcus Species and the Fluconazole Exposure Prediction Model.

Open Forum Infect Dis · 2019 · PMC6767974 · PMID 31420668

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an increasing trendno p-value reported

However, a recent systematic review of 4995 clinical isolates in 29 studies from 1988 to 2017 revealed that fluconazole nonsusceptible Cryptococcus neoformans and Cryptococcus gattii isolates ranged from 0%–50% with a mean prevalence of 12%, and an increasing trend over time [ 9 ].

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