A MetAP2 inhibitor blocks adipogenesis, yet improves glucose uptake in cells.

Adipocyte · 2019 · PMC6768232 · PMID 31264515

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highly significantno p-value reported

Immunoblotting for genes playing a role in cellular glucose uptake showed a dose-dependent increase in pAKT expression with 20 μM and 50 μM compound BL6 treatment ( Figure 4(e )) and a highly significant increase in Glut4 abundance for all three doses of MetAP2 inhibitor treatment ( Figures 4 and 5 (f)).

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