highly significantp < 0.01
A2B5 quantification by flow cytometry revealed a highly significant increase of A2B5 immunoreactivity in ST8SIA3-overexpressing cells as compared to the control cell line (U251-ST8SIA3: 85.13% ± 2.59%, p < 0.01; U87-ST8SIA3: 82.62% ± 1.86%, p < 0.01) and a drastic reduction of A2B5-positive cells in shST8SIA3 cells (U251-shST8SIA3: 2.7% ± 1.1%, p < 0.01; U87-shST8SIA3: 1.6% ± 0.2%, p < 0.01) ( Figure 1 D,G).