Comparative Transcriptomic and Lipidomic Analyses of Human Male and Female Meibomian Glands Reveal Common Signature Genes of Meibogenesis.

Only a handful of genes were identified as being expressed highly differentially and having highly significant p -values, none of which encoded any known enzymes involved in metabolism and storage of lipids in general, and meibogenesis specifically [ 10 , 11 ], except for ACADVL and SMDP3 with F/M LFC of (−2.9) and a borderline (+2.1), correspondingly.

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