Barely Significant
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Nutraceutical Supplements in the Thyroid Setting: Health Benefits beyond Basic Nutrition.

Nutrients · 2019 · PMC6770945 · PMID 31540254

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highly significantno p-value reported
The conclusion was that the six-months treatment with melatonin produced a remarkable and highly significant improvement of thyroid function, positive changes of gonadotropins towards more juvenile levels, and the abrogation of menopause-related depression.

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