Parvalbumin Promoter Methylation Altered in Major Depressive Disorder.

Although no significant difference of HAMD-17 score was observed between non-suicidal MDD and suicidal-MDD groups (Z = -1.212; p = 0.225), a highly significant correlation with HAMD-17 score was apparent for CpG4 methylation (r = -0.287; p = 0.005), but not for CpG2 (r = -0.024; p = 0.820) (Figure 5 ).

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