The relationship between F E NO and attack is replicated by the correlation between airway eosinophilia and asthma attack; asthma treatment guided by airway eosinophilia reduces asthma attacks in adults [ 17 ] and children [ 18 ] (the latter with borderline significance in a small study).
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Reducing Asthma Attacks in Children using Exhaled Nitric Oxide as a biomarker to inform treatment strategy: a randomised trial (RAACENO).
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