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Establishment of an <i>in vitro</i> model of cultured viable human, porcine and canine skin and comparison of different media supplements.

PeerJ · 2019 · PMC6778665 · PMID 31592353

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an increasing trendno p-value reported
In order to facilitate and abbreviate the pharmaceutical development process, an increasing trend to the transfer from in vivo to in vitro research has been observed during the last few decades ( Kim, Stein & O’Hare, 2004 ; Tsang & Bhatia, 2004 ).

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