Genetic Analysis Of <i>ABCA1</i> Gene Of Primary Glaucoma In Jordanian Arab Population.

On the other hand, a case-control study of the (rs2472493 and rs2487032) SNPs near the ABCA1 gene among 1122 PACG subjects and 1311 healthy controls in a Han Chinese cohort showed no significant association in the distribution of allele frequencies in PACG, 8 although they showed highly significant association in POAG. 24 – 26 Even though both PACG and POAG are subtypes of glaucoma, they share many similar clinical characteristics, but the genetic susceptibility might be different on the same candidate gene. 8 In this study, we genotyped two SNPs located upstream of ABCA1 gene (rs2472493 and rs2487032) in a Jordanian Arab glaucoma patients.

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