One-Hour Esophageal String Test: A Nonendoscopic Minimally Invasive Test That Accurately Detects Disease Activity in Eosinophilic Esophagitis.

Outcome measures for the EST (string) compared to biopsies (extracts) for the two-biomarker model for subjects with active EoE, inactive EoE, or normal esophagus are shown in Table 2 for the combination of Eot3 with each of the EDGPs studied; these combinations showed highly significant and comparable outcome measures including probability, sensitivity, specificity, positive predictive value (PPV), negative predictive value (NPV), and area under the curve (AUC), further supporting use of the EST for capturing active esophageal eosinophilic inflammation among all study patients performing the EST.

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