Gonadal mosaicism of large terminal de novo duplication and deletion in siblings with variable intellectual disability phenotypes.

Mol Genet Genomic Med · 2019 · PMC6785528 · PMID 31475484

Europe PMC DOI

hedged sentence

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closest p · 0.0× alpha

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boldest claim

The sentences

highly significantP < 2.1 × 10 –6actually significant

Candidate gene analysis Our Gene Ontology pathway enrichment analysis of the impacted genes within the CNV breakpoints identified “detection of chemical stimulus involved in sensory perception (GO:0050907)” and “nervous system process” (GO:0050877) pathways to be highly significant (FDR P < 2.1 × 10 –6 ) and (FDR P < 9.0 × 10 –3 ) after correction.

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