Cell-free DNA levels of twins and sibling pairs indicate individuality and possible use as a personalized biomarker.

PLoS One · 2019 · PMC6786590 · PMID 31600277

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closest p · 0.0× alpha

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highly significantp-value = 6.278e-07actually significant

Even though there were highly significant differences between the cfDNA of healthy and breast cancers (p-value = 6.278e-07) and healthy and ovarian cancers (p-value = 2.708e-11), on the individual levels there were many overlapping cfDNA values between cancer-free individuals and cancer patients.

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