Atrial high-rate episodes: prevalence, stroke risk, implications for management, and clinical gaps in evidence.

Europace · 2019 · PMC6788209 · PMID 31377792

Europe PMC DOI

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highly significantno p-value reported

48 , 49 Prospective randomized studies from the late 1980s reported a dramatic and highly significant reduction in stroke in patients with AF treated with warfarin.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.