Barely Significant
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The percentage of high-grade prostatic adenocarcinoma in prostate biopsies significantly improves on Grade Groups in the prediction of prostate cancer death.

Histopathology · 2019 · PMC6790619 · PMID 31032963

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hedged sentence
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The sentences

highly significantP < 2.2 × 10 −16actually significant
The overall percentage of HG disease was highly significant, with a hazard ratio of 4.45 for the interquartile range (95% confidence interval 3.30–6.01, P < 2.2 × 10 −16 ), and was similar to the percentage of HG disease seen in the worst core.

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