Metastases with definitive pathological diagnosis but no detectable primary tumor: A surveillance epidemiology and end results-based study.

Cancer Med · 2019 · PMC6792521 · PMID 31407505

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a decreasing trendno p-value reported

Our results show an increasing trend in the incidence of type 2 CUP and a decreasing trend in the incidence of classic CUP (type 1).

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an increasing trendno p-value reported

Type 2 CUP shows an increasing trend, while type 1 shows the opposite.

also in 63,971 other papers

Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.