Quantitation and modeling of post-translational modifications in a therapeutic monoclonal antibody from single- and multiple-dose monkey pharmacokinetic studies using mass spectrometry.

PLoS One · 2019 · PMC6795451 · PMID 31618250

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an increasing trendno p-value reported

As a result, the relative abundance of deamidation at Asn site 2 and 3 exhibited a saw-tooth pattern with an increasing trend over time ( Fig 3B ).

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