Barely Significant
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Expression and predictive value of miR-489 and miR-21 in melanoma metastasis.

World J Clin Cases · 2019 · PMC6795714 · PMID 31624741

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a decreasing trendno p-value reported
At present, although there are no specific studies on TNM stage and metastasis of melanoma and miR-489 and miR-21, there are reports on miRNAs and melanoma, which suggest that the expression of miRNA-125b detected by qRT-PCR technology shows a decreasing trend in serum of melanoma patients.

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