Metabolic Programming of Macrophages: Implications in the Pathogenesis of Granulomatous Disease.

Front Immunol · 2019 · PMC6797840 · PMID 31681260

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Based on inverse proportions of eosinophils, macrophage numbers also appear to be higher in the granulomas of naturally-infected wild water rats ( Nectomys squamipes ) than in chronic granulomas of experimentally-infected mice ( 133 ), indicating that there may be significant differences between experimental and natural granuloma formation that must be taken into account.

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