There are concerns that the positive and negative connections may be significant in themselves; however, the sum may be low and indicate a near-zero connection strength, and too many small negative connections can cancel out strong connections during the summation and result in near-zero connections or vice versa .
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Functional Connectivity of Language Regions of Stroke Patients with Expressive Aphasia During Real-Time Functional Magnetic Resonance Imaging Based Neurofeedback.
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