Actively priming autophagic cell death with novel transferrin receptor-targeted nanomedicine for synergistic chemotherapy against breast cancer.

A P -value less than 0.05 is considered statistically significant, while P less than 0.01 was considered highly significant. 3 Results and discussion 3.1 Preparation and characterization of transferrin receptor-targeted micelles 3.1.1 Synthesis of 7peptide conjugated PEG-DSPE polymer 7pep was conjugated to the distal end of PEG through a nucleophilic substitution reaction ( Supporting Information Scheme S1 ).

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