Real-time PCR studies revealed a highly significant increase of iNOS in hRPE cells after co-stimulation with IFN-γ, IL-1β, and TNFα (Fig. 2 c), which was not affected by the addition of the competitive inhibitor N G MMA as expected (Fig. 2 c).
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Interplay between IDO1 and iNOS in human retinal pigment epithelial cells.
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