Statistical significance was observed in the level of fasting blood glucose when pigs reached 10 weeks of age, and hIAPP pigs had increased fasting blood glucose with an increasing trend and reached 8.95 ± 0.55 mmol/L at 6 months, showing the symptom of hyperglycemia (Fig. 5e ).
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Preparation of a new type 2 diabetic miniature pig model via the CRISPR/Cas9 system.
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