A continuous-time hidden Markov model for cancer surveillance using serum biomarkers with application to hepatocellular carcinoma.

Metron · 2019 · PMC6820468 · PMID 31708595

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an increasing trendno p-value reported

To study this we use a Bayesian hierarchical model to permit the identification of the potential change in trend of the score (from no temporal trend to an increasing trend) corresponding to the onset of a tumour.

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