Barely Significant
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E2F1 acetylation directs p300/CBP-mediated histone acetylation at DNA double-strand breaks to facilitate repair.

Nat Commun · 2019 · PMC6821830 · PMID 31666529

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hedged sentence
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closest p · 0.0× alpha
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boldest claim

The sentences

highly significantP < 0.0001actually significant
The difference in the survival rates between genotypes is highly significant with values of P < 0.0001.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.