Barely Significant
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Host-range shift of H3N8 canine influenza virus: a phylodynamic analysis of its origin and adaptation from equine to canine host.

Vet Res · 2019 · PMC6822366 · PMID 31666126

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The sentences

an increasing trendp < 0.0001actually significant
As shown in Figure 8 , there was an increasing trend in the U content over time ( p < 0.0001) for all gene segments in both viruses, with the exception of the HA segment of H3N8 CIV, in which the U content gradually decreased over time.

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