highly significantP < 0.01
Only the daily diary question regarding nasal stuffiness on day 3 of Study 1 was highly significant ( P < 0.01).
Only the daily diary question regarding nasal stuffiness on day 3 of Study 1 was highly significant ( P < 0.01).
Subgroup Analyses A number of responses to various questions on the daily diary items and NRQLQ were marginally significant in different prespecified subgroups, stratified by age (18–24 years, 25–54 years, and ≥ 55 years), Berlin Questionnaire score [≥ 2 (subjects at risk for sleep apnoea) and < 2 (not at risk)], and Epworth Sleepiness Scale score (≤ 10 and > 10).