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Sinomenine sensitizes human gastric cancer cells to cisplatin through negative regulation of PI3K/AKT/Wnt signaling pathway.

Anticancer Drugs · 2019 · PMC6824511 · PMID 31609766

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an increasing trendno p-value reported
Recent cancer statistics have shown an increasing trend on the incidence and mortality rate of gastric cancer, with estimated 27 510 new cases and 11 140 deaths [ 20 ].

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.