Telomere length and aging-related outcomes in humans: A Mendelian randomization study in 261,000 older participants.

Aging Cell · 2019 · PMC6826144 · PMID 31444995

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an increasing trendno p-value reported

Both studies reported an increasing trend in systolic blood pressure with genetically increased telomere length.

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a decreasing trendno p-value reported

Regarding common aging measures, for example, hand grip strength and the 49‐item frailty index (Figure 4 ), a decreasing trend was found consistently across methods and there was little evidence of pleiotropy for low hand grip strength.

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