Tests of the chromatographic theory of olfaction with highly soluble odors: a combined electro-olfactogram and computational fluid dynamics study in the mouse.

Methyl isonicotinate, an odor that is more mucus soluble than heptanoic acid ( Table 1 ), had a positive trend (W=36, n =8, P <0.01) in average EOG responses moving from caudal to rostral recording locations resulting in a significant inverse correlation with odorant flux (r=−0.91; P <0.01; Fig. 2 B iii ).

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