The Targeting of RNA Polymerase I Transcription Using CX-5461 in Combination with Radiation Enhances Tumour Cell Killing Effects in Human Solid Cancers.

Cancers (Basel) · 2019 · PMC6826960 · PMID 31557908

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highly significantno p-value reported

Regarding apoptosis (caspase-dependent PCDI) we were able to demonstrate a clear dose-dependent increase in CaSki cells following treatment with CX-5461, which was also apparent at highly significant levels following combinations of drug and X-rays.

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