Quantitative Imaging of White and Gray Matter Remyelination in the Cuprizone Demyelination Model Using the Macromolecular Proton Fraction.

Cells · 2019 · PMC6830095 · PMID 31590363

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Second, this study shows that both imaging and histological outcomes in the cuprizone model should be assessed not only for the corpus callosum but also for different gray matter structures (cortex, striatum, hippocampus), where the effects of both demyelination and remyelination are highly significant.

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