High-definition transcranial direct current stimulation-An open-label pilot intervention in alleviating depressive symptoms and cognitive deficits in late-life depression.

Clinical response Despite an increasing trend in the percentage of participants with clinical response in terms of their depressive severity (ie, more than a 50% reduction in total HAM‐D scores from the baseline), over time ( t 0 vs t 1 = 46.67%, t 0 vs t 2 = 80.00%, t 0 vs t 3 = 85.71%, t 0 vs t 4 = 66.67%), the effect of time was not significant (Cochran's Q : χ 2 (3) = 5.50, P = .139). 3.2.3.

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