Regulation of CHD2 expression by the Chaserr long noncoding RNA gene is essential for viability.

Nat Commun · 2019 · PMC6841665 · PMID 31704914

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Indeed, we found a mild yet highly significant correlation between changes in gene expression in Chaserr –/– mEFs and the distance to the TTS of the closest tandem upstream gene (Spearman R = 0.2, P < 2 × 10 −15 ), with the effect observed mostly when the distance was shorter than ~6 kb (Fig. 4e ).

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