Tumor cell expression of B7-H4 correlates with higher frequencies of tumor-infiltrating APCs and higher CXCL17 expression in human epithelial ovarian cancer.

CXCL17 was the only chemokine or chemokine receptor in the top 250 most significantly differentially expressed genes and showed a highly significant positive correlation with B7-H4 mRNA expression (Spearman Rho = 0.53; p = 2.2 x 10 −16 ) (Supplementary Figure S8).

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Under these conditions, an unexpected trend toward improved survival in patients with B7-H4 high tumors was observed; however, the differences did not reach significance (Supplementary Figure S2).

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