<i>C1R</i> Mutations Trigger Constitutive Complement 1 Activation in Periodontal Ehlers-Danlos Syndrome.

Front Immunol · 2019 · PMC6848165 · PMID 31749804

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highly significantno p-value reported

After addition of C4 to the harvested cell culture supernatant, highly significant C4 activation was detected in fibroblast supernatant of pEDS patients (median 40.79 ng/ml, interquartile range 29.51–54.08).

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