highly significantP < 0.0001
From a technical point of view, we achieved a highly significant intra‐ (Spearmans ρ = 0.8729, P < 0.0001***) or interobserver (Spearmans ρ = 0.8577, P < 0.0001***) agreement of manual GAM quantification.
From a technical point of view, we achieved a highly significant intra‐ (Spearmans ρ = 0.8729, P < 0.0001***) or interobserver (Spearmans ρ = 0.8577, P < 0.0001***) agreement of manual GAM quantification.
Within our cohort of DNA‐methylation‐based classified IDH‐wild‐type GBMs, we could likewise only detect a nonsignificant trend toward lower Iba1‐positive GAM levels in patients with — discordant to the DNA‐methylation profiling — lower histopathological grading (Figure S3 E).