Transcriptomic Signatures Predict Regulators of Drug Synergy and Clinical Regimen Efficacy against Tuberculosis.

We found a highly significant degree of correlation between the INDIGO-MTB interaction scores and the sputum culture conversion rates for the corresponding combinations ( R = −0.55 ± 0.04, P ∼ 10 −5 ; see Fig. 3A and Table S1D ).

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