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The JAK inhibitor tofacitinib ameliorates immune‑mediated liver injury in mice.

Mol Med Rep · 2019 · PMC6854585 · PMID 31638166

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a decreasing trendno p-value reported
However, the p-STAT1 levels revealed a decreasing trend at the 48-h time point, indicating that the JAK1/STAT1 pathway plays an important role in the progression and development of ConA-induced acute liver injury in mice.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.