Barely Significant
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Janus kinase inhibitors for the treatment of rheumatoid arthritis demonstrate similar profiles of in vitro cytokine receptor inhibition.

Pharmacol Res Perspect · 2019 · PMC6857076 · PMID 31832202

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may be significantno p-value reported
Indeed, time above IC 50 may be significant. 39 One observation with tofacitinib dosed QD vs BID suggests that some JAK effects may be more sensitive to daily drug holiday.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.