Identification of candidate cancer drivers by integrative Epi-DNA and Gene Expression (iEDGE) data analysis.

Sci Rep · 2019 · PMC6858347 · PMID 31729402

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highly significantP-value = 3.53e-5actually significant

In the TCGA breast cancer dataset, we found a highly significant enrichment of Rank-1 cis genes among genes with amplification-driven gene dependencies (Fisher test one-sided P-value = 3.53e-5).

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