highly significantP = 1.47 E − 50
Recent large-scale meta-analyses of PD GWAS have described a highly significant peak at chromosome 4 (latest PD GWAS, chr4:951947 (hg19)/rs34311866, P = 1.47 E − 50, odds ratio [OR] = 1.232, standard error [SE] = 0.014) ( 3 , 4 ).