Activation and In Vivo Evolution of the MAIT Cell Transcriptome in Mice and Humans Reveals Tissue Repair Functionality.

Analysis of TCR genes over-represented in MAIT cells confirmed highly significant, selective use of TRAV1-2 with T cell receptor beta variable (TRBV)6-4, TRBV6-1, and TRBV20-1 in humans and Trbv13-3 with Trav1 and Traj33 in mice, in MAIT cells compared to naive CD8 T cells, as expected ( Lepore et al., 2014 , Porcelli et al., 1993 , Reantragoon et al., 2013 , Tilloy et al., 1999 ) ( Table S4 ; Figures S2 and S3 ).

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