highly significantp = 0.001
As shown in Figures 5A,B , two-way ANOVA revealed a highly significant difference in cell viability and LDH leakage by genotype (cell viability: F 1 , 17 = 19.825, p = 0.001; LDH leakage: F 1 , 17 = 45.246, p < 0.001), treatment (cell viability: F 2 , 17 = 74.184, p < 0.001; LDH leakage: F 2 , 17 = 293.169, p < 0.001), and genotype × treatment (cell viability: F 2 , 17 = 17.137, p < 0.001; LDH leakage: F 2 , 17 = 51.483, p < 0.001).