Moreover, even we have conducted our research in two pancreatic cancer cell lines, we will test the treatment response of coix seed extract and gemcitabine in a larger pancreatic cancer cell panels since the ABC transporters-based drug efflux in chemo-resistance may not be significant to all pancreatic cancers.
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Coix Seed Extract Enhances the Anti-Pancreatic Cancer Efficacy of Gemcitabine through Regulating ABCB1- and ABCG2-Mediated Drug Efflux: A Bioluminescent Pharmacokinetic and Pharmacodynamic Study.
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