Inhibitory Effect of Two Traditional Chinese Medicine Monomers, Berberine and Matrine, on the Quorum Sensing System of Antimicrobial-Resistant <i>Escherichia coli</i>.

Front Microbiol · 2019 · PMC6863804 · PMID 31798551

Europe PMC DOI

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highly significantno p-value reported

The drug-resistant strain 2 had the strongest biofilm formation ability, followed by the drug-resistant strain 3, and the difference was highly significant when compared with the negative control group.

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extremely significantno p-value reported

We hypothesized that due to the extremely significant inhibition of the cell division genes ftsE and ftsQ , E. coli could not reach a certain density of growth in the medium.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.