Barely Significant
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Circulating Th17.1 cells as candidate for the prediction of therapeutic response to abatacept in patients with rheumatoid arthritis: An exploratory research.

PLoS One · 2019 · PMC6867595 · PMID 31747403

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may be significantno p-value reported
Furthermore, the balance between the co-stimulatory signals from CD28 and co-inhibitory signals from CTLA-4 in each Th cell subset after ABA treatment may be significant.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.