Improved chemotherapy modeling with RAG-based immune deficient mice.

PLoS One · 2019 · PMC6867639 · PMID 31747424

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an observed trendno p-value reported

In a cohort of relapsed pediatric ALL patients, while pegaspargase demonstrated a prolonged half-life, there was an observed trend towards lower asparagine clearance in the CNS [ 48 ].

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.